關於「3CL protease」標籤，搜尋引擎有相關的訊息討論：

Lead compounds for the development of SARS-CoV-2 3CL protease ...。

2021年4月1日 · The essential SARS-CoV-2 3CL protease is of interest as a drug target. ... being loaded onto a Superdex 10/300 GL column in 50 mM Tris-HCl, ...。

Inhibition of the 3CL Protease and SARS-CoV-2 Replication by ...。

2021年6月17日 · -E.P. performed the docking inves- tigations; A.P. performed the analysis of dalcetrapib-ester/thiol conversion; F.L.-T. managed the research ...。

Mechanism of the Maturation Process of SARS-CoV 3CL Protease。

Viral maturation requires a main protease (3CLpro) to cleave the ... Center (NSRRC) (Taiwan) and Taiwan beamline BL12B2 in SPring-8 (Japan), respectively.。

Inhibitors of Coronavirus 3CL Proteases Protect Cells from Protease ...。

2021年6月24日 · Dittmar M, Lee JS, Whig K, Segrist E, Li M, Kamalia B, Castellana L, Ayyanathan K, Cardenas-Diaz FL, Morrisey EE, Truitt R, Yang W, Jurado K, ...。

3C-like protease inhibitors block coronavirus replication in vitro and ...。

2 X-ray cocrystal structures of compounds with coronavirus 3CL proteases. ... 10/300 GL size exclusion column equilibrated with 20 mM tris (pH 8.0) and 100 ...。

3CL Protease (SARS-CoV-1 / SARS-CoV-2) Substrate - BPS ...。

3CL Protease Substrate Sensitive internally quenched fluorogenic (FRET) substrate for SARS main protease with a Km value of 17 μM and a kcat value of 1.9 ...： 。

Biochemical screening for SARS-CoV-2 main protease inhibitors。

2020年10月6日 · This cysteine protease acts by processing the viruses' precursor ... main protease Mpro (also termed 3CLpro because of its homology to the ...。

CoV 3C-like (main) protease | Coronavirus - IUPHAR/BPS Guide to ...。

The SARS-CoV main protease (Mpro) is a 306 amino acid cysteine protease that ... Description: Crystal structure of SARS coronavirus 3CL protease inhibitor ...。

Scutellaria baicalensis extract and baicalein inhibit replication of ...。

2021年1月24日 · The 3C-like protease (3CLpro) of SARS-CoV-2 is a preferred target for broad ... A colorimetric substrate Thr-Ser-Ala-Val-Leu-Gln-pNA (GL ...。

SARS-CoV-2 Mpro inhibitors with antiviral activity - AAAS - Science。

2021年3月26日 · This cleaving process is performed by two viral proteases: main protease (Mpro, also named 3CL protease) and papain-like protease (7). These ...