【問題】5 cap and poly-A tail ?推薦回答

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Mind your caps and Poly A tails | NEB。

Enzyme-based capping (left) is performed after in vitro transcription using 5´-triphosphate RNA, GTP, and S-adenosylmethionine (SAM). Cap 0 mRNA can be ...: 。

Ending the message: poly(A) signals then and now - NCBI。

Polyadenylation [poly(A)] signals (PAS) are a defining feature of eukaryotic protein-coding ... The cap at the 5′ end of mRNA is depicted as a red ball.: tw | tw。

Polyadenylation and nuclear export of mRNAs - NCBI。

2019年1月25日 · During these nuclear steps in the gene expression pathway, pre-RNA transcripts are modified by the addition of 5′ caps and 3′ poly(A) tails, ...: tw | tw。

Poly(A) Tail Length-dependent Stabilization of GAP-43 mRNA by the ...。

To radiolabel the body of the RNA, RNAs were transcribed in vitro in the presence of 1 mm cap analog 7mG(5′)ppp(5′)G (Invitrogen) and of [α-32P]UTP (PerkinElmer ...: tw | tw。

Phosphodiester modifications in mRNA poly(A) tail prevent ...。

2020年8月20日 · Modifications of the 5′ cap may lead to augmented mRNA stability and ... Poly(A) tails undergo gradual shortening (deadenylation) in an ...。

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Inhibition of Poly(A)-binding protein with a synthetic RNA mimic ...。

2018年1月2日 · Regulated cytoplasmic polyadenylation serves crucial roles in the developing ... factors associated with the 5′ 7-methyl guanosine cap.。

Polyadenylation - Wikipedia。

The level of access to the 5′ cap and poly(A) tail is important in controlling how soon the mRNA is degraded. PARN deadenylates less if the RNA is bound by the ...: 。

The molecular basis of coupling between poly(A)-tail length and ...。

2021年1月19日 · PABPCs have high affinity to poly(A) sequences in vitro (Kd ∼5 nM for ... the interaction between eIF4E and the mRNA 5′ cap and facilitate ...。

Variable 3'polyadenylation of Wheat yellow mosaic virus and its ...。

2019年2月20日 · Polyadenylation influences many aspects of mRNA as well as viral RNA. ... cooperation with the 5′ cap mediated by some host factors [15].


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