【問題】Why it is so difficult to target a pathogenic virus without damaging the host's cells ?推薦回答

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Virus–Receptor Interactions: The Key to Cellular Invasion - NCBI。

Viruses are obligate intracellular pathogens that rely on host cell ... The numerous functions of viral receptors all coordinate virus targeting to the ...。

Factors Affecting the Tissue Damaging Consequences of Viral ...。

2019年10月4日 · Since viruses are obligate intracellular parasites that require host cells to replicate and assemble infectious progeny, the question arises ...。

Intracellular Pathogens: Host Immunity and Microbial Persistence ...。

In influenza A virus infection, IL-22 production by iNKT cells was involved in control of lung epithelial damage but had no direct effect on viral replication [ ...。

How do antibiotics kill bacterial cells but not human cells? - Scientific ...。

2006年3月13日 · The result is a very fragile cell wall that bursts, killing the bacterium. No harm comes to the human host because penicillin does not ...: difficult 。

Technologies to address antimicrobial resistance | PNAS。

2018年12月17日 · The failure to develop antibiotics with a novel mechanism was not ... To be effective at the target, more antibiotic is needed on the ...。

Why are there so many drugs to kill bacteria, but so few to tackle ...。

2020年5月8日 · This makes it hard to kill viruses without killing our own cells in the process. Remdesivir is one antiviral researchers are investigating to ...: pathogenic 。

will we discover new antibiotics to combat pathogenic bacteria in time?。

The opinion of many clinicians, that new antibiotics are not required so ... of drugs available to treat other diseases (viral infections, tumours, etc).。

Review Targeting Bacterial Central Metabolism for Drug Development。

2014年11月20日 · Bacterial infection alters the metabolic flux of host cells through ... Such a remodeling of central carbon metabolism in both viruses and ...。

Nanotechnology for COVID-19: Therapeutics and Vaccine Research。

2020年6月22日 · (112) Some other targets that are considered for neutralizing antibody ... the host interaction: (a) Qβ[Gal3] with no virus interaction, ...。

Endocytosis of Viruses and Bacteria - Cold Spring Harbor ...。

Of the many pathogens that infect humans and animals, a large number use cells of the host organism as protected sites for replication. To reach the relevant ...


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